MESOGEL NANO AND MESOSTRUCTURED ANTIMICROBIAL COATINGS FOR ANODIZED-BASED PROSTHESES AND SOL-GEL COATINGS
In this research project, nanostructured and mesostructured antibacterial coatings will be developed on Ti-6Al-4V alloys, which is the most widely used material for the manufacture of prostheses due to its resistance to corrosion, good mechanical properties and great biocompatibility. 2.5 million hip and knee implants are implanted each year. One of the main problems with prosthetic implantation is the infection processes that take place in approximately 2 percent of cases. This supposes a great economic damage by having to replace the implant, in addition to the need for new surgical procedures; what affects the quality of life of the patient. For this reason, this research project aims to solve this problem through the development of nanostructured and mesostructured antibacterial coatings. For this, TiO2 nanotube coatings will be generated using the anodizing technique and nano and mesostructured coatings using the sol-gel technique. Bactericidal agents (mainly Ag nanoparticles) will be introduced into the pores generated in these nano / mesostructures to minimize the possible risk of infections. The pores will be sealed by molecular gates, which will allow a controlled release when a certain stimulus is given (pH, temperature, etc.).
The objective of the project is to develop nano and mesostructured coatings with antibacterial functionality on TiAl6V4 prostheses to reduce the incidence of joint prosthesis infection.
Objective Sectors by Activity
METAL INDUSTRY - Number of target companies: 76 (36 of the Valencian Community)
Thanks to its support and signature of the "declaration of participation" the project has been funded.
SURGIVAL CO, SAU
COMPANIES DIFFUSION R&D PROJECTS
They want to know first-hand the evolution of the project, and its progress to the final result.
COMPANIES TRANSFER KNOWLEDGE
They will implement technologies, develop strategies or look for new models based on the results.